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Transarterial Chemoembolization

Case - 1: middle aged man came with a large (15 x12X13cm ) hepatocellular carcinoma (HCC)  in right lobe of liver. Due to its large size, it was not amenable for treatment with alcohol ablation or radiofrequency ablation. It was decided to be treated with chemoembolization where anticancer drug is injected into the tumour and then the blood vessel supplying the tumour is occluded. 
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Large HCC as seen on the angiogram.
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Transarterial chemoembolization(TACE) in progress. 
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Cast of  anticancer drug with lipiodol is seen. Lipiodol is supposed to have affinity for liver cancer cells. It carries anticancer drug to cancer cells . Blocking the feeding artery cuts off the blood supply to the tumour and avoids washing away of the drug.
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Follow up CT scan after 4 months shows gross reduction in the size of tumour . Lipiodol is still seen in the tumour.

 

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